The discovery of a new polymer that may allow development of an effective insulin pill was reported at a recent meeting of the American Chemical Society. When the polymer is used as a pill coating, it allows insulin to get into the bloodstream without being destroyed by the digestive system. So far it has only been tested in animals. Some experts question whether insulin in pill form will prove useful, since dosing is so critical and often variable.

Meanwhile, an inhaled form of insulin is being tested in clinical trials. A recent study found that patients with type 1 diabetes using the inhaled insulin maintained glycemic control during a 12-week trial. They preferred using inhaled insulin to subcutaneous insulin. The report's authors concluded, "Inhaled insulin may offer the first practical, noninvasive alternative to insulin injections."

At least initially, inhaled insulin would be used in conjunction with injectable insulin. Questions about the long-term effects on the lungs remain unanswered.

Related information: Treatment - Insulin | Advances in Diabetes

Sources:

• Elliott VS. Scientists strive to spare diabetics from the needle. AMA: AMedNews. Sept. 17, 2001.
• Gerber RA, Cappelleri JC, Kourides IA, et al. Treatment satisfaction with inhaled insulin in patients with type 1 diabetes. Diabetes Care, Sept. 2001;24:1556-1559.